AM-4668

Catalog No.: A21778

GPR40 agonist

AM-4668

AM-4668 Chemical Structure

CAS NO. 1011531-27-3

AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively.

Availability: In stock

Package Price Qty
5 mg
$252.00
10 mg
$434.00
50 mg
$1,288.00
100 mg
$2,576.00
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Biological Activity

AM-4668 is a GPR40 agonist for type 2 diabetes. EC50s of 3.6 nM and 36 nM for GPR40 in A9 cells (GPR40 IP3 assay) and CHO cells (GPR40 aequorin assay), respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.47 mL 102.36 mL 204.72 mL
0.5 mM 4.09 mL 20.47 mL 40.94 mL
1 mM 2.05 mL 10.24 mL 20.47 mL
5 mM 0.41 mL 2.05 mL 4.09 mL

*The above data is based on the productmolecular weight 488.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21778
Actions Agonist
CAS No. 1011531-27-3
Formula C24H19F3N2O4S
M. Wt 488.48
Purity >98%
Synonyms AM 4668; AM4668
SMILES OC(C[[email protected]](C1=NOC=C1)C(C=C2)=CC=C2OCC(S3)=C(C)N=C3C4=CC=C(C(F)(F)F)C=C4)=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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