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AM404

Anandamide Inhibitor

AM404 is a potent inhibitor of anandamide reuptake, effectively blocking its transport with IC50 values in the low micromolar range. This compound demonstrates relaxation of rat isolated hepatic arteries that have been contracted with Phenylephrine, exhibiting a pEC50 value of 7.4, which corresponds to an EC50 of 0.04 μM. Additionally, AM404 shows neuroprotective effects, making it a valuable tool in the study of cannabinoid signaling and related therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	183718-77-6
Applications	Anandamide Inhibitor
Formula	C₂₆H₃₇NO₂
Molecular Weight	395.58
SMILES	CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(NC1=CC=C(O)C=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.