Fig. 1 · Structure

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AM4299B

Thiol Protease Inhibitor

AM4299B is a potent inhibitor of thiol proteases, specifically targeting bovine spleen cathepsin B, human kidney cathepsin L, and papain, with IC50 values of 0.7, 0.5, and 20 μM, respectively. This compound is valuable in research related to osteoporosis and demonstrates potential applications as an antiparasitic agent. Its selectivity and efficacy make it an important tool for studying protease functions and their roles in various biological processes.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 160825-49-0
Applications Thiol Protease Inhibitor
Formula C16H27N3O7
Molecular Weight 373.40
SMILES
N[C@@H](CCCCNC([C@H](CC(C)C)NC(C1OC1C(O)=O)=O)=O)C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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