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- Uchida D, .et al. Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells, Oncol Rep, 2018, Jul;40(1):303-308 PMID: 29749473
- Mamoru Morimoto, .et al. Enhancement of the CXCL12/CXCR4 axis due to acquisition of resistance in pancreatic cancer: effect of CXCR4 antagonists, BMC Cancer, 2016, 16: 305 PMID: 27175473
Biological Activity
AMD 070 is a CXCR4 chemokine receptor antagonist.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.61 mL | 143.06 mL | 286.12 mL |
| 0.5 mM | 5.72 mL | 28.61 mL | 57.22 mL |
| 1 mM | 2.86 mL | 14.31 mL | 28.61 mL |
| 5 mM | 0.57 mL | 2.86 mL | 5.72 mL |
*The above data is based on the productmolecular weight 349.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11315 |
|---|---|
| Actions | Antagonist |
| CAS No. | 558447-26-0 |
| Formula | C21H27N5 |
| M. Wt | 349.5 |
| Purity | >98% |
| Synonyms | AMD070, AMD-070 |
| SMILES | C1C[[email protected]@H](C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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