AMD 070

Catalog No.: A11315

CXCR4 antagonist

AMD 070

AMD 070 Chemical Structure

CAS NO. 558447-26-0

AMD 070 is a CXCR4 chemokine receptor antagonist.

Availability: In stock

Package Price Qty
5 mg
$126.00
10 mg
$214.00
25 mg
$378.00
50 mg
$630.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Uchida D, .et al. Effect of a novel orally bioavailable CXCR4 inhibitor, AMD070, on the metastasis of oral cancer cells, Oncol Rep, 2018, Jul;40(1):303-308 PMID: 29749473
  • Mamoru Morimoto, .et al. Enhancement of the CXCL12/CXCR4 axis due to acquisition of resistance in pancreatic cancer: effect of CXCR4 antagonists, BMC Cancer, 2016, 16: 305 PMID: 27175473

Biological Activity

AMD 070 is a CXCR4 chemokine receptor antagonist.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.61 mL 143.06 mL 286.12 mL
0.5 mM 5.72 mL 28.61 mL 57.22 mL
1 mM 2.86 mL 14.31 mL 28.61 mL
5 mM 0.57 mL 2.86 mL 5.72 mL

*The above data is based on the productmolecular weight 349.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11315
Actions Antagonist
CAS No. 558447-26-0
Formula C21H27N5
M. Wt 349.5
Solubility DMSO
Purity >98%
Synonyms AMD070, AMD-070
SMILES C1C[[email protected]@H](C2=C(C1)C=CC=N2)N(CCCCN)CC3=NC4=CC=CC=C4N3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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