Fig. 1 · Structure
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Ametantrone acetate
Antitumor Agent
Ametantrone acetate, an antitumor agent, exerts its effects primarily through the inhibition of topoisomerase II. This compound induces covalent cross-linking of DNA, which disrupts DNA replication and transcription, leading to enhanced anticancer activity. Research applications of Ametantrone acetate include studies focused on its pharmacokinetics and metabolic pathways as well as investigations into its efficacy against various cancer types.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 70711-40-9 |
| Applications | Antitumor Agent |
| Formula | C26H36N4O8 |
| Molecular Weight | 532.59 |
| Synonyms | NSC 196473 acetate; NSC 290813 acetate |
| SMILES | O=C1C2=C(C(C3=C(C=CC(NCCNCCO)=C13)NCCNCCO)=O)C=CC=C2.CC(O)=O.CC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.