AMG-076 free base

Catalog No.: A61620
MCHR1 Antagonist
AMG-076 free base is a selective antagonist of the Melanin-Concentrating Hormone Receptor 1 (MCHR1). It has been shown to significantly reduce body weight gain in non-obese mice subjected to a high-fat diet, as well as in diet-induced obese (DIO) mice. This compound is valuable for research into obesity and metabolic disorders, providing insights into the therapeutic potential of targeting MCHR1 in weight management.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAMG-076 free base is a selective antagonist of the Melanin-Concentrating Hormone Receptor 1 (MCHR1). It has been shown to significantly reduce body weight gain in non-obese mice subjected to a high-fat diet, as well as in diet-induced obese (DIO) mice. This compound is valuable for research into obesity and metabolic disorders, providing insights into the therapeutic potential of targeting MCHR1 in weight management.
Product Information
Catalog NumA61620
FormulaC26H33F3N2O2
Molecular Weight462.55
CAS Number693823-79-9
SMILESO=C(C1(CCN2CC[C@]3([H])CC(NC4=C5C=C(C(F)(F)F)C=C4)=C5[C@H](C)[C@@]3([H])C2)CCCCC1)O
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