AMG-076

Catalog No.: A61622
MCHR1 Antagonist
AMG-076 is a selective antagonist of the melanin-concentrating hormone receptor-1 (MCHR1). This compound has demonstrated significant reductions in body weight gain in both nonobese mice on a high-fat diet and in diet-induced obese (DIO) mice. AMG-076 serves as a valuable tool for studying obesity and metabolic disorders in preclinical research.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionAMG-076 is a selective antagonist of the melanin-concentrating hormone receptor-1 (MCHR1). This compound has demonstrated significant reductions in body weight gain in both nonobese mice on a high-fat diet and in diet-induced obese (DIO) mice. AMG-076 serves as a valuable tool for studying obesity and metabolic disorders in preclinical research.
Product Information
Catalog NumA61622
FormulaC32H39F3N2O5S
Molecular Weight620.72
CAS Number1001438-96-5
SMILESO=C(O)C1(CCCCC1)CCN2CC[C@@]3(CC4=C([C@@H]([C@]3(C2)[H])C)C(C=C(C=C5)C(F)(F)F)=C5N4)[H].O=S(C6=CC=CC=C6)(O)=O
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