AMG 337

Catalog No.: A16400

MET inhibitor

AMG 337

AMG 337 Chemical Structure

CAS NO. 1173699-31-4

AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor.

Availability: In stock

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5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $160.00

Special Price $128.00

50 mg

Regular Price: $480.00

Special Price $384.00

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Biological Activity

AMG 337 is an oral, small molecule, ATP-competitive, highly selective inhibitor of the MET receptor.
In vitro DMSO 92 mg/mL (198.5 mM)
Water Insoluble
Ethanol 92 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.58 mL 107.88 mL 215.77 mL
0.5 mM 4.32 mL 21.58 mL 43.15 mL
1 mM 2.16 mL 10.79 mL 21.58 mL
5 mM 0.43 mL 2.16 mL 4.32 mL

*The above data is based on the productmolecular weight 463.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16400
Actions Inhibitor
CAS No. 1173699-31-4
Formula C23H22FN7O3
M. Wt 463.46
Purity >98%
Synonyms AMG337, AMG-337
SMILES CN1N=CC(C2=CN3C([[email protected]@H](C)N4C=CC(N=CC(OCCOC)=C5)=C5C4=O)=NN=C3C(F)=C2)=C1

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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