Fig. 1 · Structure
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Amifostine sodium
Cytoprotective Agent
Amifostine sodium is a cytoprotective agent that exhibits radioprotective activity through its action as a free radical scavenger. It induces splenic vasodilation and has the potential to modulate autonomic ganglia activity. Amifostine sodium is primarily utilized in clinical settings to prevent cisplatin-induced ototoxicity and other forms of acute cellular damage resulting from chemotherapy or radiation exposure.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 59178-37-9 |
| Applications | Cytoprotective Agent |
| Formula | C5H13N2Na2O3PS |
| Molecular Weight | 258.19 |
| Synonyms | WR2721 sodium |
| SMILES | O=P(SCCNCCCN)(O[Na])O[Na] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.