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Amine-PEG8-Val-Cit-PAB-MMAE

Drug-linker Conjugate

Amine-PEG8-Val-Cit-PAB-MMAE is a drug-linker conjugate designed for use in antibody-drug conjugates (ADCs). This compound combines a PEG8 linker with the cytotoxic agent MMAE, facilitating targeted delivery of chemotherapy to cancer cells. Its applications are particularly relevant in the study of various cancers, including gastric cancer, colon cancer, and lung adenocarcinoma, making it a valuable tool for cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2879227-86-6
Applications	Drug-linker Conjugate
Formula	C₇₇H₁₃₁N₁₁O₂₁
Molecular Weight	1546.93
SMILES	O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OCC3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCOCCOCCOCCOCCN)=O)=O)=O)=O)=O)=O)=O)OC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.