Fig. 1 · Structure
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Amisometradine
Aminouracil Diuretic
Amisometradine is an orally active aminouracil diuretic primarily targeting sodium and chloride excretion. It demonstrates diuretic potency approximately 40% that of Mersalyl, contributing significant therapeutic effects in heart failure models while maintaining good tolerance for long-term use. Compared to other diuretics, Amisometradine is associated with fewer gastrointestinal reactions, and its minor side effects, which include nausea and tinnitus, are generally not accompanied by proteinuria or relevant blood and urine abnormalities. This compound serves as a valuable reagent for investigating diuretic mechanisms and heart failure treatments.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 550-28-7 |
| Applications | Aminouracil Diuretic |
| Formula | C9H13N3O2 |
| Molecular Weight | 195.22 |
| SMILES | O=C1C=C(N)N(C(=O)N1C)CC(=C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.