Amitriptyline HCl

Catalog No.: A16404

Amitriptyline HCl

Amitriptyline HCl Chemical Structure

CAS NO. 549-18-8

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Availability: In stock

Package Price Qty
50 mg
$60.00
100 mg
$100.00
500 mg
$300.00
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Biological Activity

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.
In vitro DMSO 56 mg/mL (178.42 mM)
Water 56 mg/mL (178.42 mM)
Ethanol 13 mg/mL (41.42 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.86 mL 159.31 mL 318.61 mL
0.5 mM 6.37 mL 31.86 mL 63.72 mL
1 mM 3.19 mL 15.93 mL 31.86 mL
5 mM 0.64 mL 3.19 mL 6.37 mL

*The above data is based on the productmolecular weight 313.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16404
CAS No. 549-18-8
Formula C20H23N.HCl
M. Wt 313.86
Solubility DMSO
Purity >98%
SMILES CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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