Amitriptyline HCl

Name: Amitriptyline HCl
Brand: Adooq Bioscience
SKU: A16404
Rating: 5 (288 reviews)

Catalog No.: A16404

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

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Grouped product items
Size	Price	Stock
1g	$20.00	In stock
5g	$30.00	In stock
Bulk Size	Bulk Discount

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Data Sheet SDS

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Biological Activity

Description

Amitriptyline inhibits serotonin receptor, norepinephrine receptor, 5-HT4, 5-HT2 and sigma 1 receptor with IC50 of 3.45 nM, 13.3 nM, 7.31 nM, 235 nM and 287 nM, respectively.

Targets

Target	Value

Product Information

Catalog Num	A16404
Formula	C20H23N.HCl
Molecular Weight	313.86
CAS Number	549-18-8
SMILES	CN(C)CCC=C1C2=CC=CC=C2CCC3=CC=CC=C31.Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	56 mg/mL (178.42 mM)
	Water	13 mg/mL (41.42 mM)
	Ethanol	56 mg/mL (178.42 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.86 mL	159.31 mL	318.61 mL
0.5 mM	6.37 mL	31.86 mL	63.72 mL
1 mM	3.19 mL	15.93 mL	31.86 mL
5 mM	0.64 mL	3.19 mL	6.37 mL

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