Fig. 1 · Structure

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Amoxapine-d8

Stable Isotope

Amoxapine-d8 is a deuterium-labeled derivative of Amoxapine, a compound known for its role as a norepinephrine reuptake inhibitor and 5-HT2/5-HT3 receptor antagonist. This stable isotope is valuable for pharmacokinetic studies and metabolic research involving depression and other neuropsychiatric disorders. Additionally, Amoxapine has demonstrated antibacterial activity and can enhance macrophage-mediated killing of mycobacterium through autophagy induction while providing cytoprotection.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1189671-27-9
Applications Stable Isotope
Formula C17H8D8ClN3O
Molecular Weight 321.83
Synonyms CL-67772-d8
SMILES
ClC1=CC=C2OC3=CC=CC=C3N=C(N4C([2H])([2H])C([2H])([2H])NC([2H])([2H])C4([2H])[2H])C2=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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