AMP-PCP is a potent ATP analogue that selectively binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 μM. This binding promotes the formation of the active homodimeric structure of Hsp90, enhancing its chaperone activity. AMP-PCP is valuable in research applications focused on understanding the molecular mechanisms of Hsp90 modulation and its role in protein folding and stability in various cellular contexts.
AMP-PCP is a potent ATP analogue that selectively binds to the N-terminal domain of Hsp90 with a Kd value of 3.8 μM. This binding promotes the formation of the active homodimeric structure of Hsp90, enhancing its chaperone activity. AMP-PCP is valuable in research applications focused on understanding the molecular mechanisms of Hsp90 modulation and its role in protein folding and stability in various cellular contexts.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
