Fig. 1 · Structure
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AMT-NHS
RNA-protein Crosslinker
AMT-NHS is an RNA-protein crosslinker that targets RNA bases and primary amines of proteins through its psoralen derivative and N-hydroxysuccinimide ester functionality. This reagent effectively penetrates living yeast cells, allowing for specific crosslinking of Cbf5 to H/ACA snoRNAs. AMT-NHS is capable of inducing varied crosslinking patterns, targeting both single- and double-stranded RNA regions. It is a valuable tool for capturing and analyzing diverse RNA-protein interactions within cellular contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2925268-86-4 |
| Applications | RNA-protein Crosslinker |
| Formula | C22H21NO7S |
| Molecular Weight | 443.47 |
| SMILES | O=C(ON1C(CCC1=O)=O)CCSCC2=C(C)OC(C(C)=C3O4)=C2C=C3C(C)=CC4=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.