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Amubarvimab
Amubarvimab (BRII-196) is a human IgG1 monoclonal antibody designed to target distinct, non-competing epitopes on the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. It exhibits a binding affinity with a dissociation constant (K_D) of 5.88 nM, demonstrating potent neutralization capabilities against various SARS-CoV-2 variants. This specificity and efficacy make Amubarvimab a valuable tool for research into the mechanisms of viral entry and immune evasion.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2509447-07-6 |
| Synonyms | BRII-196 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.