Fig. 1 · Structure
Documents & Downloads
AN-988
CRM1 Inhibitor
AN-988 is a covalent inhibitor of CRM1 (chromosomal region maintenance 1), which plays a critical role in the nuclear export of various proteins. This compound effectively disrupts the CRM1-mediated export pathway, leading to the accumulation of target proteins in the nucleus. AN-988 is valuable for research applications focused on cancer biology, antiviral therapy, and cellular signaling pathways, providing insights into the therapeutic potential of CRM1 inhibition.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 340304-55-4 |
| Applications | CRM1 Inhibitor |
| Formula | C22H22N2O4S |
| Molecular Weight | 410.49 |
| SMILES | O=C(C1=CC=CC(COC2=CC=C(/C=C3S/C(N(CC)C/3=O)=N/CC)C=C2)=C1)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.