Fig. 1 · Structure

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Anabaseine

AChR Agonist

Anabaseine is a potent agonist of various nicotinic acetylcholine receptors (AChRs), including the neuromuscular α12β1γδ or α12β1γɛ and α7 subtypes. This brain-penetrant alkaloid toxin exhibits key biological activity as a stimulator of these receptors, making it valuable for research into neuromuscular transmission and neurobiology. Additionally, Anabaseine acts as a weak partial agonist at α4β2 nAChRs, further broadening its applications in studying cholinergic signaling pathways.

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Specifications

Manufacturer Adooq Bioscience
Actions Agonist
CAS Number 3471-05-4
Applications AChR Agonist
Formula C10H12N2
Molecular Weight 160.22
SMILES
C1(C2=CC=CN=C2)=NCCCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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