Anabasine hydrochloride is a potent agonist of nicotinic acetylcholine receptors (nAChRs). This alkaloid, derived from tobacco (Nicotiana), functions as a full agonist, inducing depolarization in TE671 cells that endogenously express human fetal muscle-type nAChRs (EC50 = 0.7 µM). Anabasine hydrochloride is relevant for research applications in neurobiology and toxicology, particularly in studies exploring nAChR signaling and muscle contraction mechanisms.
Anabasine hydrochloride is a potent agonist of nicotinic acetylcholine receptors (nAChRs). This alkaloid, derived from tobacco (Nicotiana), functions as a full agonist, inducing depolarization in TE671 cells that endogenously express human fetal muscle-type nAChRs (EC50 = 0.7 µM). Anabasine hydrochloride is relevant for research applications in neurobiology and toxicology, particularly in studies exploring nAChR signaling and muscle contraction mechanisms.
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