Fig. 1 · Structure
Documents & Downloads
(±)-Anatoxin A fumarate
Nicotinic Receptor Agonist
(±)-Anatoxin A fumarate is a potent agonist of nicotinic receptors, specifically engaging α4β2 and α7 subtypes with Ki values of 1.25 nM and 1.84 μM, respectively. This compound effectively stimulates [3H]-dopamine release in rat striatal synaptosomes, demonstrating an EC50 of 134 nM. Its biological activity makes it a valuable tool for studying neurotransmitter release and nicotinic receptor function, while also highlighting its toxic effects on aquatic organisms.
In Stock
Free Aliquoting for Your Order
Tell us your preferred amount per vial. We’ll confirm the options.
Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1219922-30-1 |
| Applications | Nicotinic Receptor Agonist |
| Formula | C14H19NO5 |
| Molecular Weight | 281.30 |
| SMILES | CC(C1=CCCC2CCC1N2)=O.O=C(O)/C=C/C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.