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Androst-16-en-3-ol

GABAA Receptor Positive Modulator

Androst-16-en-3-ol is a positive allosteric modulator of GABAA receptors, influencing neurotransmission in the central nervous system. This compound is known for its anxiolytic, antidepressant, and anticonvulsant properties, evidenced through behavioral studies in mice. Additionally, it serves as a pheromone, eliciting mating responses in estrous sows, and is present in human biological fluids such as urine and sweat. Its modulation of GABAA receptors positions Androst-16-en-3-ol as a significant reagent for investigating neuropharmacological mechanisms and exploring potential therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Modulator
CAS Number	7148-51-8
Applications	GABAA Receptor Positive Modulator
Formula	C₁₉H₃₀O
Molecular Weight	274.44
Synonyms	3β-Androstenol
SMILES	C[C@@]12[C@]3([H])[C@](CC[C@@]1([H])C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C=CC4)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.