Angiotensin II (1-4), human is an endogenous peptide that functions as an agonist for the angiotensin receptor. It primarily binds to the AT II type 1 (AT1) receptor, activating GPCRs in vascular smooth muscle cells, which leads to an increase in intracellular calcium levels. Additionally, Angiotensin II (1-4) influences the sodium/hydrogen exchanger in the proximal tubules of the kidney, playing a critical role in regulating blood pressure and fluid balance. This peptide is valuable for research applications related to cardiovascular function and renal physiology.
Angiotensin II (1-4), human is an endogenous peptide that functions as an agonist for the angiotensin receptor. It primarily binds to the AT II type 1 (AT1) receptor, activating GPCRs in vascular smooth muscle cells, which leads to an increase in intracellular calcium levels. Additionally, Angiotensin II (1-4) influences the sodium/hydrogen exchanger in the proximal tubules of the kidney, playing a critical role in regulating blood pressure and fluid balance. This peptide is valuable for research applications related to cardiovascular function and renal physiology.
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