AnnH31 is a selective inhibitor of Dyrk1A with an IC50 value of 81 nM. In addition, AnnH31 inhibits monoamine oxidase A (MAO-A) at an IC50 of 3.2 μM. This compound has been shown to reduce cell viability in HeLa, PC12, and SH-SY5Y cell lines, making it a valuable tool for research focused on neurodegeneration and cancer biology.
AnnH31 is a selective inhibitor of Dyrk1A with an IC50 value of 81 nM. In addition, AnnH31 inhibits monoamine oxidase A (MAO-A) at an IC50 of 3.2 μM. This compound has been shown to reduce cell viability in HeLa, PC12, and SH-SY5Y cell lines, making it a valuable tool for research focused on neurodegeneration and cancer biology.
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