Fig. 1 · Structure
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Ansornitinib
Antifibrotic Agent
Ansornitinib is an orally active dual kinase inhibitor that targets platelet-derived growth factor receptor (PDGFR) and vascular endothelial growth factor receptor (VEGFR2). It exhibits significant antifibrotic activity and is applicable in the study of lung, liver, kidney, and gastrointestinal fibrotic diseases. This compound serves as a valuable tool for researchers investigating fibrotic mechanisms and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1448874-96-1 |
| Applications | Antifibrotic Agent |
| Formula | C30H32N6O4 |
| Molecular Weight | 540.61 |
| Synonyms | ANG-3070 |
| SMILES | CN(CC1)CCN1CC(N(C)C(C=C2)=CC=C2N/C(C3=CC=CC=C3)=C4C5=CC=C(C(OC)=O)N=C5NC/4=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.