Fig. 1 · Structure
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Anthglutin
Glutathione S-transferase Inhibitor
Anthglutin is a potent inhibitor of glutathione S-transferase, derived from cultures of Penicillium oxalicum. It exhibits Ki values of 5.7 μM for porcine kidney enzyme, 18.3 μM for human kidney enzyme, 13.6 μM for human liver soluble enzyme, and 10.2 μM for the conjugated enzyme. This compound is valuable for research into the role of glutathione S-transferases in detoxification processes and the study of their impact on cellular signaling pathways. Additionally, Anthglutin has been shown to exert no significant influence on the intestinal absorption of methionine in rat models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 69168-09-8 |
| Applications | Glutathione S-transferase Inhibitor |
| Formula | C12H15N3O5 |
| Molecular Weight | 281.26 |
| SMILES | O=C(O)C1=CC=CC=C1NNC(CC[C@H](N)C(O)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.