Fig. 1 · Structure
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Anti-aging agent 1
Anti-aging
Anti-aging agent 1 is a piperlongumine derivative designed to target senescent cells. It demonstrates a significant enhancement in senolytic activity, exhibiting a 50-fold increase in efficacy against senescent WI-38 fibroblasts compared to its parent compound. This reagent is suitable for research applications focused on aging and cellular senescence, providing valuable insights into potential therapeutic strategies for age-related conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1884611-28-2 |
| Applications | Anti-aging |
| Formula | C16H16ClNO3 |
| Molecular Weight | 305.76 |
| SMILES | COC1=CC=C(/C=C/C(N2CCCC=C(Cl)C2=O)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.