Fig. 1 · Structure
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Antibacterial agent 124
ProRS Inhibitor
Antibacterial agent 124 is a potent inhibitor of bacterial prolyl-tRNA synthetase (ProRS) with an IC50 of 0.18 μM specifically against Staphylococcus aureus ProRS (SaProRS). This compound demonstrates significant antibacterial activity, making it a valuable tool for research into the mechanisms of bacterial protein synthesis and antibiotic resistance. Its use in further studies may facilitate the development of novel therapeutic strategies targeting bacterial infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2304448-00-6 |
| Applications | ProRS Inhibitor |
| Formula | C16H17ClFN3O2 |
| Molecular Weight | 337.78 |
| SMILES | O=C(CN1C=NC2=CC(Cl)=C(C=C2C1=O)F)C[C@@H]3CCCCN3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.