Fig. 1 · Structure

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Antibacterial agent 227

SerRS Inhibitor

Antibacterial agent 227 is a selective inhibitor of Seryl-tRNA synthetase (SerRS). This compound demonstrates significant antibacterial activity against planktonic and biofilm cultures of Staphylococcus aureus 25923, with a minimum inhibitory concentration (MIC) of 32 µg/ml. Antibacterial agent 227 holds promise as an effective antiseptic for combating multidrug-resistant, biofilm-forming S. aureus isolates in research applications.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 301304-67-6
Applications SerRS Inhibitor
Formula C12H13N5O3
Molecular Weight 275.26
SMILES
O=C(N1)C(C)=NN=C1N/N=C/C2=C(O)C(OC)=CC=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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