Fig. 1 · Structure
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Antibacterial agent 81
Transcription Inhibitor
Antibacterial Agent 81 is a potent DNA transcription inhibitor that targets bacterial transcription processes. It demonstrates significant antibacterial activity against Staphylococcus aureus USA300 and Mycobacterium smegmatis ATCC14468, with minimum inhibitory concentration (MIC) values of 12.5 μM and 7.8 μM, respectively. This compound is valuable for research focused on bacterial infections and the development of effective antimicrobial therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2873395-27-6 |
| Applications | Transcription Inhibitor |
| Formula | C33H28N2O8 |
| Molecular Weight | 580.58 |
| SMILES | COC1=CC=C(C=C1)C2=C(C3=C(C=C(C(C(C(NC4=CC=CC=C4C(O)=O)=O)=O)=C3N2)OC)OC)C5=CC=C(C=C5)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.