Documents & Downloads

Anticancer agent 128

IAP Inhibitor

Anticancer agent 128 is an IAP (Inhibitor of Apoptosis Protein) inhibitor that covalently targets the BIR3 domains of XIAP, cIAP1, and cIAP2. This compound exhibits potent biological activity, with IC50 values of 24.9 nM, 19.3 nM, and 10.3 nM against these targets, respectively. It is pivotal for research applications involving apoptosis regulation and cancer treatment strategies, offering a promising avenue for therapeutic development.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2941243-62-3
Applications	IAP Inhibitor
Formula	C₂₆H₃₈N₄O₄
Molecular Weight	470.60
SMILES	O=C(N1[C@H](C(N[C@H]2C(C=CC=C3O)=C3CC2)=O)CCC1)[C@H](C4CCCCC4)NC([C@H](C)NC)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.