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Anticancer agent 131

HCT-116 Inhibitor

Anticancer agent 131 is an HCT-116 inhibitor characterized as a γ-lactam-fused pyridone derivative. This compound demonstrates significant anticancer activity, exhibiting high cytotoxicity against HCT-116 cells with an IC50 value of 5.59 μM. It serves as a valuable tool for cancer research, particularly in studies focused on targeting the HCT-116 cell line.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2864443-47-8
Applications	HCT-116 Inhibitor
Formula	C₃₃H₂₄ClN₃O₅
Molecular Weight	578.01
SMILES	ClC1=CC=C(O)C(C2=C(C3=CC=C([N+]([O-])=O)C=C3)C(N(C4=CC=CC=C4)C5=C2CN(C6=C(C)C=CC=C6C)C5=O)=O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.