Fig. 1 · Structure

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Anticancer agent 133

Antimetastatic Agent

Anticancer agent 133 (Rh2) functions as an antimetastatic agent by exhibiting cytotoxic properties and promoting both apoptosis and autophagy. This compound effectively induces cell cycle arrest in cancer cells, inhibiting their proliferation. Additionally, anticancer agent 133 suppresses cell metastasis through the downregulation of EGFR expression, which is mediated by FAK-regulated integrin β1. This makes it a valuable tool for research in cancer therapy and metastasis inhibition.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2758905-51-8
Applications Antimetastatic Agent
Formula C24H19Cl3N5ORh
Molecular Weight 602.71
SMILES
Cl[Rh]12(Cl)([N]#CC)[N]3=C(C(N2C4=CC=CC=C4)=O)C(Cl)=CC=C3N5C(C6=CC=CC=C6)=CC(C)=[N]51

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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