Fig. 1 · Structure

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Anticancer agent 164

Anticancer Agent

Anticancer Agent 164 is a potent compound designed to target and induce apoptosis in human chronic myeloid leukemia (CML) cells, specifically the K562 cell line. This agent significantly reduces protein phosphorylation within the PI3K/Akt signaling pathway, thereby promoting cell death. Additionally, it inhibits cell proliferation by suppressing the MEK/ERK pathway, showcasing its potential in colorectal cancer research applications.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2235393-30-1
Applications Anticancer Agent
Formula C21H23F3N8O2S2
Molecular Weight 540.58
SMILES
O=C(NC1=CC=C(C(F)(F)F)C=C1)NC2=NN=C(SC3=NC=NC(NCCCN4CCOCC4)=C3)S2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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