Fig. 1 · Structure
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Anticancer agent 188
Anticancer Agent
Anticancer Agent 188 (Compound D43) is a potent inhibitor of DNA synthesis, specifically targeting triple-negative breast cancer (TNBC) cells. Its primary mechanism induces cell cycle arrest at the G2/M phase, effectively disrupting cancer cell proliferation. Additionally, Anticancer Agent 188 exhibits significant anti-cancer activity through the induction of reactive oxygen species (ROS)-mediated apoptosis and DNA damage, making it a valuable tool for cancer research and therapeutic investigations.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1207377-56-7 |
| Applications | Anticancer Agent |
| Formula | C13H10FN5O2 |
| Molecular Weight | 287.25 |
| SMILES | CN1C(C2=NC(C3=C(F)C=CC=C3)=N1)=NC(N(C)C2=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.