Fig. 1 · Structure
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Anticancer agent 230
Anticancer Agent
Anticancer agent 230 is a specific activator of caseinolytic protease P (ClpP) that exhibits notable anticancer properties. This compound effectively promotes the degradation of mitochondrial proteins in triple-negative breast cancer cell lines, such as SUM159 and MDA-MB-231, in a time-dependent manner. Its mechanism suggests potential applications in the study of cancer cell metabolism and the development of targeted therapeutics for challenging breast cancer subtypes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2485052-87-5 |
| Applications | Anticancer Agent |
| Formula | C22H19ClN4O |
| Molecular Weight | 390.87 |
| SMILES | N#CC1=CC=CC(CN(C2)CCC(N=CN3CC4=CC=C(Cl)C=C4)=C2C3=O)=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.