Fig. 1 · Structure
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Anticancer agent 231
Protein kinase Inhibitor
Anticancer agent 231 is a selective tyrosine protein kinase inhibitor, exhibiting an IC50 value of 3.95 μM. It demonstrates significant biological activity by inhibiting cell viability, proliferation, and migration in triple-negative breast cancer (TNBC) cells through modulation of the EGFR-ERK 1/2 signaling pathway. This compound is poised to provide valuable insights in the therapeutic strategies for TNBC treatment.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 128519-30-2 |
| Applications | Protein kinase Inhibitor |
| Formula | C23H22ClN3 |
| Molecular Weight | 375.89 |
| SMILES | ClC1=CC=C(C2=NN(C3=CC=CC=C3)C(C4=CC=C(N(C)C)C=C4)C2)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.