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Anticancer agent 29

Anticancer Agent

Anticancer Agent 29 (Compd E/Z-6f) is a potent inhibitor of cyclin-dependent kinases (CDKs), specifically targeting CDK2, CDK1, CDK4, and CDK6, with IC50 values of 0.054 μM, 0.127 μM, 0.129 μM, and 0.396 μM, respectively. This compound exhibits significant antiproliferative activity, making it a valuable tool for exploring cancer cell cycle regulation and therapeutic strategies. Its selectivity and potency in inhibiting key CDKs present opportunities for research in cancer treatment and drug development.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2907774-89-2
Applications	Anticancer Agent
Formula	C₂₂H₁₅ClFNO
Molecular Weight	363.81
SMILES	O=C1/C(C2=CC=CC=C2N1CC3=CC=C(C=C3)F)=C/C4=CC=C(C=C4)Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.