Fig. 1 · Structure

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Anticancer agent 300

CCND1, CDK4, CDK6, CCNE1 Modulator

Anticancer Agent 300 (compound P14) is a modulator of CCND1, CDK4, CDK6, and CCNE1, exhibiting significant anti-proliferative properties. This compound influences cell cycle regulation, induces senescence, and promotes apoptosis in cancer cells. It is applicable in research related to ER+/HER2− breast cancer and BRAF-mutant melanoma, providing valuable insights for cancer therapeutics.

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Specifications

Manufacturer Adooq Bioscience
Actions Modulator
CAS Number 1310059-06-3
Applications CCND1, CDK4, CDK6, CCNE1 Modulator
Formula C24H19N3OS2
Molecular Weight 429.56
SMILES
C12=C(SC(C3=CC(C4=CC5=C(S4)C=CC=C5)=NC(N6CCOCC6)=N3)=C2)C=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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