Fig. 1 · Structure
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Anticancer agent 57
Anticancer Agent
Anticancer agent 57 primarily acts as an anticancer agent targeting triple-negative breast cancer (TNBC) cells. It demonstrates potent inhibitory effects on MDA-MB-231, MDA-MB-468, and MCF-7 cell lines, with IC50 values ranging from 6.43 to 8.00 μM. This compound induces cell cycle arrest and significantly enhances apoptosis in these cell lines. Additionally, anticancer agent 57 effectively inhibits tumor growth in nude mice xenografted with MDA-MB-231 cells, making it a valuable tool for research into TNBC.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2408017-71-8 |
| Applications | Anticancer Agent |
| Formula | C20H21Cl2NO2 |
| Molecular Weight | 378.29 |
| SMILES | O=C(C1=CC=CC(OC)=C1)/C=C/C2=CC=C(N(CCCl)CCCl)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.