Fig. 1 · Structure

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Anticancer agent 81

Anticancer Agent

Anticancer Agent 81 (Compound 37b3) functions as a potent anticancer agent by inducing tumor cell cycle arrest and promoting apoptosis in cancer cells. This compound can be utilized as a payload for conjugation with Trastuzumab, creating the antibody-drug conjugate (ADC) T-PBA. T-PBA preserves the targeting and internalization capabilities of Trastuzumab, making it a valuable tool for targeted cancer therapy research.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2820286-56-2
Applications Anticancer Agent
Formula C46H46N6O5
Molecular Weight 762.89
SMILES
O=C1N(CCN2CCN(CCCCCOC3=C(OC)C=C4C(N=C[C@@](CC(C5=CC=C(N)C=C5)=C6)([H])N6C4=O)=C3)CC2)C(C7=CC=CC8=CC9=CC=CC=C9C1=C78)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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