Fig. 1 · Structure
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Antileishmanial agent-16
Anti-Leishmania Agent
Antileishmanial agent-16 is a potent anti-Leishmania compound that exhibits significant activity against Leishmania major promastigotes (IC50 = 0.59 µM) and amastigotes (IC50 = 0.81 µM). This agent demonstrates a favorable safety profile in VERO cells, making it an ideal candidate for further research and development in the treatment of leishmaniasis. Its efficacy against both forms of the parasite highlights its potential utility in therapeutic applications targeting Leishmania infections.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2934738-41-5 |
| Applications | Anti-Leishmania Agent |
| Formula | C27H37N5O4 |
| Molecular Weight | 495.61 |
| SMILES | CCCCOC1=CC2=C(C=C(C(O2)=O)C(NCCCCCCN3C=C(N=N3)CN4CCCC4)=O)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.