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Antimalarial agent 31

Plasmepsin X (PMX) Inhibitor

Antimalarial agent 31 is a selective inhibitor of Plasmodium falciparum plasmepsin X (PMX), a vital aspartic protease involved in the parasite's proteolytic pathway. This compound demonstrates significant antimalarial activity, making it a valuable tool for research into malaria pathogenesis and therapeutic development. Its oral bioavailability further enhances its potential for in vivo studies aimed at understanding the inhibition of PMX and its implications in treating malaria.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3033682-50-4
Applications	Plasmepsin X (PMX) Inhibitor
Formula	C₃₆H₄₇N₃O₄
Molecular Weight	585.78
SMILES	O[C@@H]([C@@H](NC(C1=CC=CC(C(N(CCC)CCCCC2)=O)=C1)=O)CC3=CC=CC2=C3)CNC(C)(C)C4=CC=CC(OC)=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.