Fig. 1 · Structure

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Antimicrobial agent-46

StSAT Inhibitor

Antimicrobial agent-46 is a potent inhibitor of Salmonella typhimurium serine acetyltransferase (StSAT), exhibiting an IC50 of 48.6 μM. This compound disrupts bacterial growth in minimal medium devoid of cysteine, targeting the cysteine biosynthesis pathway essential for bacterial persistence and adaptability. Antimicrobial agent-46 demonstrates significant antibacterial activity against the Gram-negative bacterium Escherichia coli, making it a valuable tool for research in infectious diseases and antimicrobial resistance.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 898619-81-3
Applications StSAT Inhibitor
Formula C6H3N5O3S2
Molecular Weight 257.25
SMILES
O=C(C1=CSN=N1)NC2=NC=C([N+]([O-])=O)S2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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