Fig. 1 · Structure
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Antineoplastic agent-1
Necroptosi Inducer
Antineoplastic agent-1 is a potent necroptosis inducer that acts as an alkylating and genotoxic agent, leading to significant DNA damage. Its ability to trigger irreversible harm and subsequent death of liver cells through necroptosis and apoptosis underscores its potential in cancer research. Additionally, Antineoplastic agent-1 has demonstrated the capacity to inflict alkylation damage on hematopoietic and stromal cells within the bone marrow. This compound is valuable for investigations into tumor biology and the mechanisms underlying cell death in cancer.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inducer |
| CAS Number | 738-99-8 |
| Applications | Necroptosi Inducer |
| Formula | C12H24N6O2P2 |
| Molecular Weight | 346.31 |
| SMILES | O=P(N1CC1)(N2CCN(P(N3CC3)(N4CC4)=O)CC2)N5CC5 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.