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Antiproliferative agent-72

Antiproliferative Agent

Antiproliferative agent-72 is a potent Hsp90 inhibitor with a Kd of 11 nM. It demonstrates significant antiproliferative activity, exhibiting IC50 values of 1.5 μM and 1.1 μM in HCT116 and NCI-N87 cancer cell lines, respectively. This compound is valuable for cancer research, particularly in studies focused on targeting heat shock protein 90 pathways to inhibit tumor growth.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1052646-54-4
Applications	Antiproliferative Agent
Formula	C₂₀H₁₇Cl₂N₃O₂S
Molecular Weight	434.34
SMILES	ClC1=CC(Cl)=C2C=C1OCCCCOC3=CC=CC(SC4=NC(N)=NC2=C4)=C3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.