Fig. 1 · Structure
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Antisauvagine-30
CRF2 Receptor Antagonist
Antisauvagine-30 is a potent, competitive antagonist of the corticotropin-releasing factor receptor 2 (CRF2), exhibiting a Kd value of 1.4 nM for mouse CRF2β receptors. It demonstrates selectivity over rat CRF1 receptors, with a Kd of 153.6 nM. This compound is valuable for research applications exploring stress response mechanisms, neurobiology, and the role of CRF receptors in various physiological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 220673-95-0 |
| Applications | CRF2 Receptor Antagonist |
| Formula | C161H274N48O46S |
| Molecular Weight | 3650.26 |
| Synonyms | aSvg-30 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.