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Antitumor agent-196

Anticancer Agent

Antitumor agent-196 (Compound 6a (β, β, β)) is an artemisinin-based oligomer that exhibits potent anticancer activity, demonstrated by an IC50 of 90 nM against MCF-7 breast cancer cells. This compound promotes apoptosis through the regulation of the Bax-caspase 3 signaling pathway and induces ferroptosis by modulating key molecules, such as GPX4. Antitumor agent-196 represents a promising candidate for further investigation in cancer therapy research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2705841-17-2
Applications	Anticancer Agent
Formula	C₅₁H₈₁NO₁₅
Molecular Weight	948.19
SMILES	C[C@@H]1[C@@]2([H])[C@]34[C@@](O[C@@H]1OCCN(CCO[C@H]5O[C@@]6([H])[C@]78[C@](CC[C@H]([C@]7([H])CC[C@](O6)(OO8)C)C)([H])[C@H]5C)CCO[C@H]9O[C@@]%10([H])[C@]%11%12[C@](CC[C@H]([C@]%11([H])CC[C@](O%10)(OO%12)C)C)([H])[C@H]9C)([H])O[C@](OO3)(CC[C@@]4([H])[C@@H](CC2)C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.