Fig. 1 · Structure

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Antitumor agent-48

Antitumor Agent

Antitumor agent-48 (Compound 4a) is a 2,3-dehydrosilybin derivative that exhibits significant antitumor activity. It demonstrates cytotoxic effects on various cancer cell lines, including MCF-7, NCI-H1299, HepG2, and HT29, with IC50 values of 8.06 µM, 13.1 µM, 16.51 µM, and 12.44 µM, respectively. This compound is valuable for cancer research and therapeutic investigations aimed at understanding and combating tumor growth.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2917547-29-4
Applications Antitumor Agent
Formula C35H34N2O14
Molecular Weight 706.65
SMILES
COC1=CC(C2OC3=C(OC2CO)C=CC(C4=C(C(C5=C(C=C(C=C5O4)OC(N6CCOCC6)=O)O)=O)OC(N7CCOCC7)=O)=C3)=CC=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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