AP-7-168 is a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR). It functions by promoting β2AR homodimerization and inhibiting GRK5-mediated phosphorylation, thereby sustaining bronchorelaxation in both cell and tissue models. This compound is particularly valuable for research in inflammation and immunology, including studies related to asthma and other respiratory conditions.
AP-7-168 is a β-arrestin-biased negative allosteric modulator of the β2-adrenergic receptor (β2AR). It functions by promoting β2AR homodimerization and inhibiting GRK5-mediated phosphorylation, thereby sustaining bronchorelaxation in both cell and tissue models. This compound is particularly valuable for research in inflammation and immunology, including studies related to asthma and other respiratory conditions.
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