Fig. 1 · Structure
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AP39
Mitochondrial H2S Donor
AP39 is a mitochondrial-targeting hydrogen sulfide (H2S) donor derived from triphenylphosphonium and anethole dithiolethione. This compound elevates intracellular H2S levels, providing cytoprotective effects and preserving mitochondrial DNA integrity under oxidative stress. Research has demonstrated AP39's protective role against myocardial reperfusion injury in mouse models, as well as its potential applications in Alzheimer's disease studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1429061-80-2 |
| Applications | Mitochondrial H2S Donor |
| Formula | C37H38BrO2PS3 |
| Molecular Weight | 721.77 |
| SMILES | S=C1SSC(C2=CC=C(OC(CCCCCCCCC[P+](C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)=O)C=C2)=C1.[Br-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.